1 protein
1.1 general properties
1.2 structure
1.2.1 primary
1.2.2 secondary
1.2.3 tertiary
1.3 subcellular localization
1.4 post-translational modifications
protein
general properties
the protein contains domain of unknown function (duf4594 amino acid 185 350). protein, c15orf52, 534 amino acid long protein weighing 57.325 kda found in homo sapiens.
structure
primary
comparison of amino acid composition homo sapiens revealed amino acids differing frequencies other proteins in humans. phenylalanine, tyrosine, , asparagine found in lower frequencies other proteins in humans. glycine , arginine found @ higher frequencies other proteins in humans. isoelectric point of protein 9.457, indicating basic protein @ normal physiological ph of 7.4.
secondary
c15orf52 has coiled coil domain spanning amino acids 60-97 containing alpha helices.
tertiary
the tertiary structure of protein still unknown scientific community , debate.
subcellular localization
there no transmembrane sequences detected in c15orf52 protein. c15orf52 predicted non-cytoplasmic soluble protein found nuclear protein.
post-translational modifications
the protein has been experimentally observed phosphorylation @ serines found @ 2 locations, s201 , s392. n-terminal acetylations, c-glycosylations, glycations, leucine rich nuclear export signals, sumoylation, , pest motifs predicted across orthologs protein.
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