Fructolysis Fructose



the initial catabolism of fructose referred fructolysis, in analogy glycolysis, catabolism of glucose. in fructolysis, enzyme fructokinase produces fructose 1-phosphate, split aldolase b produce trioses dihydroxyacetone phosphate (dhap) , glyceraldehyde [1]. unlike glycolysis, in fructolysis triose glyceraldehyde lacks phosphate group. third enzyme, triokinase, therefore required phosphorylate glyceraldehyde, producing glyceraldehyde 3-phosphate. resulting trioses identical obtained in glycolysis , can enter gluconeogenic pathway glucose or glycogen synthesis, or further catabolized through lower glycolytic pathway pyruvate.







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