Route_description Interstate_64_in_Illinois

the poplar street bridge on mississippi river

i-64 enters illinois running concurrently i–55 , u.s. route 40 (us 40) on mississippi river on poplar street bridge. after splitting these highways in east st. louis, i-64 turns southeasterly , runs through st. clair, clinton, washington, , jefferson counties through rural part of illinois no major cities or intersections. major intersection outside of st. louis short concurrency i-57 near mount vernon. past this, interstate enters rural stretch through parts of jefferson, wayne, , white counties before crossing wabash river indiana.